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BRIEF HISTORY OF MISSISSIPPI COUNTY
AND
CHARLESTON, MISSOURI
“Mississippi County is a county located in the Bootheel of the U.S. state of
Missouri, with its eastern border formed by the Mississippi River. As of the
2010 census, the population was 14,358. The largest city which is also the
county seat is Charleston. Charleston was first called Matthews Prairie. The
name was changed to recognize Mr. Charles Moore in 1837. The county was
officially organized on February 14, 1845, and was named after the
Mississippi River.
Mississippi County is located in what was formerly known as "Tywappity
Bottom," a vast floodplain area bordered by the Scott County Hills on the
north, St. James Bayou on the south, the Mississippi River on the east, and
Little River on the west.”
Please click on the map of Missouri for additional information related to
Mississippi County.
